Multiple effects induced by unstable mutation in Streptomyces lavendulae.
نویسندگان
چکیده
منابع مشابه
Multiple effects induced by unstable mutation in Streptomyces lavendulae.
Arg mutants, isolated from Streptomyces lavendulae at unusually high frequencies, showed several phenotypic characteristics. The characteristics common to all arg mutants include: (1) repression of beta-lactamase production, (2) inhibition of aerial mycelium formation, (3) development of acid pH, (4) low saturation density of growth in liquid culture, (5) a decrease in antibiotic production, (6...
متن کاملStreptomyces lavendulae and Streptomyces venezuelae.
With the growing economic significance of some Streptomyces species, the necessity of establishing their precise characteristies in well-defined specific terms becomes of great theoretical and practical importance (Waksman, 1957). The purpose of this paper is to present a comparative study of the main morphological, physiological, and biochemical characteristics of cultures belonging to the Str...
متن کاملStudies on Streptomyces lavendulae.
Since the isolation of streptothricin by Waksman and Woodruff in 1942 from a strain of Streptomyces lavendulae, numerous reports have appeared concerning the ability of different actinomycetes to produce this antibiotic or closely related compounds. In most of the antibiotic screening programs, streptothricin and streptothricinlike substances are among the first to be commonly encountered as pr...
متن کاملSelf - protection Mechanism in D - Cycloserine - producing Streptomyces lavendulae
An antibiotic, D-cycloserine (DCS), inhibits the catalytic activities of alanine racemase (ALR) and D-alanylD-alanine ligase (DDL), which are necessary for the biosynthesis of the bacterial cell wall. In this study, we cloned both genes encoding ALR and DDL, designated alrS and ddlS, respectively, from DCS-producing Streptomyces lavendulae ATCC25233. Each gene product was purified to homogeneit...
متن کاملIsolation of lavendamycin, a new antibiotic from Streptomyces lavendulae.
Recently we have reported the structure determination of lavendamycin (1), a novel antibiotic closely related to streptonigrin (2) in structure (Fig. 1).1) In this paper we report the characterization of the producing culture, the fermentation conditions, the isolation of, and biological activity of 1. In the course of screening actinomycetes for the production of agents inducing lysogenic Esch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1980
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.33.420